OTNEJMQuadraat 10 pt However, at the collection stage, saliva-based detection could preserve high-demand health resources and supplies, such as personal protective equipment and nurses, says Dr. Jenisa Naidoo, chief scientific officer at the testing and laboratory firm Dynacare.
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Regular Self-collected oral fluid and nasal swabs demonstrate comparable sensitivity to clinician collected nasopharyngeal swabs for Covid-19 detection. 1.05833 mm End_head1_2line Callout_object left 0 pt August 4, 2020 (https://www.medrxiv.org/content/10.1101/2020.08.03.20167791v1).
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SubsectionTitleEnd 9.5 pt OTNEJMScalaSansLF 0 pt OTNEJMScalaSansLF 0 pt All the data used to generate this figure, including the raw cycle thresholds, are provided in Supplementary Data 1 in Supplementary Appendix 2. normal 0 pt verse text
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* OTNEJMQuadraatSmallCap CorrInstructions 0 pt author.signedby italic Paragraph Text & Page Number endstream 0 mm tablefootnote.first.double center Figure center Variation in nasopharyngeal sampling may be an explanation for false negative results, so monitoring an internal control for proper sample collection may provide an alternative evaluation technique. paragraph.first 0 pt supportedby affiliation 6col_single Meanwhile, Public Health Ontario is focused on logistical issues — Allen says some sites have tried urine containers to collect saliva, but at high volumes this "takes up too much space in a lab." paragraph During the clinical course, we observed less variation in levels of SARS-CoV-2 RNA in the saliva specimens (standard deviation, 0.98 virus RNA copies per milliliter; 95% credible interval, 0.08 to 1.98) than in the nasopharyngeal swab specimens (standard deviation, 2.01 virus RNA copies per milliliter; 95% credible interval, 1.29 to 2.70) (see Supplementary Appendix 1). tablebody_24-36 Nevertheless, public demand for more testing options is clearly on the rise and with COVID-19 cases rising as flu season approaches, various provincial and public health leaders have voiced their commitment to boosting test capacity.
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